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Synthesis and Chain-Dependent Antifungal Activity of Long-Chain 2H-Azirine-Carboxylate Esters Related to Dysidazirine
Analogues of the antifungal marine natural product (E)-dysidazirine were prepared and evaluated in broth ro-dilution assays against a panel of fungal pathogens. A simple structure-activity relationship was developed which provides insight into the mechanism of action of long-chain 2H-azirine carboxy...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834865/ https://ncbi.nlm.nih.gov/pubmed/20171099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.01.068 |
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