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Synthesis and Anti-fungal Activity of (−)-(Z)-Dysidazirine
[Image: see text] A short, flexible synthesis of the marine natural product (2R)-(Z)-dysidazirine (−)-1 has been completed. (−)-1 shows significant antifungal activity across a panel of seven human pathogens, while the structural analogue (−)-2, featuring a terminal tert-butyl group, is essentially...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635126/ https://ncbi.nlm.nih.gov/pubmed/18937483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802065d |
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