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Excess iodide decreases transcription of NIS and VEGF genes in rat FRTL-5 thyroid cells

Although it is well known that an excess of iodide suppresses thyroid function and blood flow in vivo, the underlying molecular mechanisms are not fully known. The functional effect of iodide occurs at multiple steps, which include inhibition of sodium/iodide symporter (NIS) expression, transient bl...

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Bibliografiske detaljer
Main Authors: Suzuki, Koichi, Kimura, Hiroaki, Wu, Huhehasi, Kudo, Naoko, Kim, Won Bae, Suzuki, Sayuri, Yoshida, Akio, Caturegli, Patrizio, Kohn, Leonard D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834827/
https://ncbi.nlm.nih.gov/pubmed/20132794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.01.123
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