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Isoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment

Flavin-containing monooxygenase (FMO) expression in male mouse liver is altered after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure or castration. Because TCDD is slowly eliminated from the body, we examined hepatic Fmo mRNA alterations for up to 32 days following 10 or 64 µg/kg TCDD exposure...

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Detalhes bibliográficos
Main Authors: Novick, Rachel M., Vezina, Chad M., Elfarra, Adnan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834820/
https://ncbi.nlm.nih.gov/pubmed/20036217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.12.020
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