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Differential Localization of Flavin-Containing Monooxygenase (FMO) Isoforms 1, 3, and 4 in Rat Liver and Kidney and Evidence for Expression of FMO4 in Mouse, Rat, and Human Liver and Kidney Microsomes

Flavin-containing monooxygenases (FMOs) play significant roles in the metabolism of drugs and endogenous or foreign compounds. In this study, the regional distribution of FMO isoforms 1, 3, and 4 was investigated in male Sprague-Dawley rat liver and kidney using immunohistochemistry (IHC). Rabbit po...

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Bibliografske podrobnosti
Main Authors: Novick, Rachel M., Mitzey, Ann M., Brownfield, Mark S., Elfarra, Adnan A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Pharmacology and Experimental Therapeutics 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683785/
https://ncbi.nlm.nih.gov/pubmed/19307449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.152058
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