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Mitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C(1)
BACKGROUND: Disorazoles are polyene macrodiolides isolated from a myxobacterium fermentation broth. Disorazole C(1 )was newly synthesized and found to depolymerize microtubules and cause mitotic arrest. Here we examined the cellular responses to disorazole C(1 )in both non-cancer and cancer cells an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834648/ https://ncbi.nlm.nih.gov/pubmed/20181182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-10-1 |
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