Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice

BACKGROUND: The anthracycline doxorubicin (DOX) is an effective chemotherapeutic agent used to treat pediatric cancers, but is associated with cardiotoxicity which can manifest many years after the initial exposure. To date, very little is known about the mechanism of this late onset cardiotoxicity....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Huang, Chengqun, Zhang, Xiaoxue, Ramil, Jennifer M., Rikka, Shivaji, Kim, Lucy, Lee, Youngil, Gude, Natalie A., Thistlethwaite, Patricia A., Sussman, Mark A., Gottlieb, Roberta A., Gustafsson, Åsa B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834271/
https://ncbi.nlm.nih.gov/pubmed/20100968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.902221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados