Myeloperoxidase Serves as a Redox Switch that Regulates Apoptosis in Epithelial Ovarian Cancer

OBJECTIVES: Resistance to apoptosis is a key feature of cancer cells and is believed to be regulated by nitrosonium ion (NO(+))-induced S-nitrosylation of key enzymes. Nitric oxide (NO), produced by inducible nitric oxide synthase (iNOS), is utilized by MPO to generated NO(+). We sought to investiga...

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Main Authors: Saed, Ghassan M., Ali-Fehmi, Rouba, Jiang, Zhong L., Fletcher, Nicole M., Diamond, Michael P., Abu-Soud, Husam M., Munkarah, Adnan R.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834266/
https://ncbi.nlm.nih.gov/pubmed/19962178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2009.11.004
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