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Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-κB pathway
The oncogenic potential of the HTLV-1 Tax protein involves activation of the NF-κB pathway, which depends on Tax phosphorylation, ubiquitination and sumoylation. We demonstrate that the nuclei of Tax-expressing cells, including HTLV-1 transformed T-lymphocytes, contain a pool of Tax molecules acetyl...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834172/ https://ncbi.nlm.nih.gov/pubmed/19200568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.12.043 |
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