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Studies on Polynucleotides, C A Novel Joining Reaction Catalyzed by the T4-Polynucleotide Ligase

The polynucleotide ligase isolated from T4-infected Escherichia coli was previously shown to bring about repair of breaks in the single strands of bihelical DNA. The present work shows that the enzyme can also catalyze the joining of DNA duplexes at their base-paired ends. This novel reaction occurs...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sgaramella, V., van de Sande, J. H., Khorana, H. G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1970
Fag:
Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5274471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1468
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