Mechanism of Carcinogenesis by RNA Tumor Viruses, III Formation of RNA·DNA Complex and Duplex DNA Molecules by the DNA Polymerase(s) of Avian Myeloblastosis Virus

DNA polymerase activity can be unmasked in avian myeloblastosis virus (AMV) by treatment with the nonionic detergent Nonidet P-40. Two products are formed: (1) RNA·DNA hybrid molecules and (2) duplex DNA molecules. The kinetics of dTTP incorporation into DNA are biphasic: an initial rapid reaction f...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fujinaga, Kei, Parsons, J. Thomas, Beard, J. W., Beard, Dorothy, Green, Maurice
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1970
Soggetti:	Biological Sciences: Biochemistry
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4322024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1432
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