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Mechanism of Carcinogenesis by RNA Tumor Viruses, III Formation of RNA·DNA Complex and Duplex DNA Molecules by the DNA Polymerase(s) of Avian Myeloblastosis Virus
DNA polymerase activity can be unmasked in avian myeloblastosis virus (AMV) by treatment with the nonionic detergent Nonidet P-40. Two products are formed: (1) RNA·DNA hybrid molecules and (2) duplex DNA molecules. The kinetics of dTTP incorporation into DNA are biphasic: an initial rapid reaction f...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1970
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4322024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1432 |
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