Mechanism of Carcinogenesis by RNA Tumor Viruses, III Formation of RNA·DNA Complex and Duplex DNA Molecules by the DNA Polymerase(s) of Avian Myeloblastosis Virus

DNA polymerase activity can be unmasked in avian myeloblastosis virus (AMV) by treatment with the nonionic detergent Nonidet P-40. Two products are formed: (1) RNA·DNA hybrid molecules and (2) duplex DNA molecules. The kinetics of dTTP incorporation into DNA are biphasic: an initial rapid reaction f...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fujinaga, Kei, Parsons, J. Thomas, Beard, J. W., Beard, Dorothy, Green, Maurice
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1970
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4322024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1432
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