Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

Glucocorticoids exert multiple anti-inflammatory activities, one of which is the inhibition of transcription dependent on the nuclear factor (NF)-κB. It has been suggested that the effect of dexamethasone (DEX), a glucocorticoid analog, is attributed to an increased production of the inhibitory IκB...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	De Bosscher, Karolien, Schmitz, M. Lienhard, Vanden Berghe, Wim, Plaisance, Stéphane, Fiers, Walter, Haegeman, Guy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28335/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.13504
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