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Toll-Like Receptor Ligands Directly Promote Activated CD4(+) T Cell Survival

Toll-like receptor (TLR) engagement by pathogen-associated molecular patterns (PAMPs) is an important mechanism for optimal cellular immune responses. APC TLR engagement indirectly enhances activated CD4(+) T cell proliferation, differentiation, and survival by promoting the up-regulation of costimu...

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Autori principali: Gelman, Andrew E., Zhang, Jidong, Choi, Yongwon, Turka, Laurence A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833313/
https://ncbi.nlm.nih.gov/pubmed/15128790
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