Downregulation of Epidermal Growth Factor Receptor Expression Contributes to α-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines

RRR-α-tocopherol derivative α-TEA (RRR-α-tocopherol ether-linked acetic acid analog) has been shown to be a potent antitumor agent both in vivo and in vitro. In this study, we investigated the effects of α-TEA on the expression of epidermal growth factor receptor (EGFR) family members, ErbB1, 2 and...

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Bibliografski detalji
Glavni autori: Shun, Ming-Chieh, Yu, Weiping, Park, Sook-Kyung, Sanders, Bob G., Kline, Kimberly
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833311/
https://ncbi.nlm.nih.gov/pubmed/20224651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/824571
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