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High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer

BACKGROUND: The Toll-like receptor (TLR) 4 signalling pathway has been shown to have oncogenic effects in vitro and in vivo. To demonstrate the role of TLR4 signalling in colon tumourigenesis, we examined the expression of TLR4 and myeloid differentiation factor 88 (MyD88) in colorectal cancer (CRC)...

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Hlavní autoři: Wang, E L, Qian, Z R, Nakasono, M, Tanahashi, T, Yoshimoto, K, Bando, Y, Kudo, E, Shimada, M, Sano, T
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833250/
https://ncbi.nlm.nih.gov/pubmed/20145615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605558
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