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Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma

BACKGROUND: Many kinds of solid tumour have heterogeneously a hypoxic environment. Tumour hypoxia reported to be associated with more aggressive tumour phenotypes such as high metastatic ability and resistance to various anti-cancer therapies which may lead to a poorer prognosis. However, the mechan...

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Main Authors: Kato, Y, Yashiro, M, Noda, S, Tendo, M, Kashiwagi, S, Doi, Y, Nishii, T, Matsuoka, J, Fuyuhiro, Y, Shinto, O, Sawada, T, Ohira, M, Hirakawa, K
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833244/
https://ncbi.nlm.nih.gov/pubmed/20145613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605543
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