Hypoxia Stimulates the EMT of Gastric Cancer Cells through Autocrine TGFβ Signaling

Epithelial mesenchymal transition (EMT) is considered to be correlated with malignancy of cancer cells and responsible for cancer invasion and metastasis. We previously reported that distant metastasis was associated with hypoxia in gastric cancer. We therefore investigated the effect of hypoxic con...

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Autores principales: Matsuoka, Junko, Yashiro, Masakazu, Doi, Yosuke, Fuyuhiro, Yuhiko, Kato, Yukihiro, Shinto, Osamu, Noda, Satoru, Kashiwagi, Shinichiro, Aomatsu, Naoki, Hirakawa, Toshiki, Hasegawa, Tsuyoshi, Shimizu, Kiyoshi, Shimizu, Toshiyuki, Miwa, Atsushi, Yamada, Nobuya, Sawada, Tetsuji, Hirakawa, Kosei
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656884/
https://ncbi.nlm.nih.gov/pubmed/23690936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062310
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