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Phosphorylation of Human Tristetraprolin in Response to Its Interaction with the Cbl Interacting Protein CIN85

BACKGROUND: Tristetraprolin (TTP) is the prototype member of a family of CCCH tandem zinc finger proteins and is considered to be an anti-inflammatory protein in mammals. TTP plays a critical role in the decay of tumor necrosis factor alpha (TNF) mRNA, among others, by binding AU-rich RNA elements i...

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Autors principals: Kedar, Vishram P., Darby, Martyn K., Williams, Jason G., Blackshear, Perry J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833206/
https://ncbi.nlm.nih.gov/pubmed/20221403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009588
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