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Purification of a Specific tRNA by Sepharose-Bound Enzyme

A new procedure for measuring binding of tRNA to aminoacyl-tRNA synthetases is described. The purified isoleucyl-tRNA synthetase from Escherichia coli can be covalently bound to activated Sepharose with retention of approximately 40% of the original enzymatic activity. If crude tRNA is passed throug...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Denburg, Jeffrey, DeLuca, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283312/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4943171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.2.1057
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