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Effect of Loss of Thymidine Kinase Activity on the Tumorigenicity of Clones of SV40-Transformed Hamster Cells

Cells deficient in the enzyme thymidine kinase were derived from transplantable SV40-transformed hamster cells. The resultant cell lines were less transplantable when inoculated into hamsters. Tumors which did arise from such cells had prolonged latent periods and were found to contain a mixture of...

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Bibliographic Details
Main Authors: Rothschild, Henry, Black, Paul H.
Format: Artigo
Language:Inglês
Published: 1970
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC283310/
https://ncbi.nlm.nih.gov/pubmed/4331716
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