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Effect of Loss of Thymidine Kinase Activity on the Tumorigenicity of Clones of SV40-Transformed Hamster Cells

Cells deficient in the enzyme thymidine kinase were derived from transplantable SV40-transformed hamster cells. The resultant cell lines were less transplantable when inoculated into hamsters. Tumors which did arise from such cells had prolonged latent periods and were found to contain a mixture of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Rothschild, Henry, Black, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1970
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283310/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4331716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.2.1042
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