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Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
BACKGROUND: Selective inhibition of the BCR-ABL tyrosine kinase by RNA interference has been demonstrated in leukemic cells. We, therefore, evaluated specific BCR-ABL small interfering RNA silencing in BCR-ABL-positive cell lines, including those resistant to imatinib and particularly those with the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833068/ https://ncbi.nlm.nih.gov/pubmed/20207846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.016063 |
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