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Apical Surface Expression of Aspartic Protease Plasmepsin 4, a Potential Transmission-blocking Target of the Plasmodium Ookinete

To invade its definitive host, the mosquito, the malaria parasite must cross the midgut peritrophic matrix that is composed of chitin cross-linked by chitin-binding proteins and then develop into an oocyst on the midgut basal lamina. Previous evidence indicates that Plasmodium ookinete-secreted chit...

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Detalhes bibliográficos
Main Authors: Li, Fengwu, Patra, Kailash P., Yowell, Charles A., Dame, John B., Chin, Karen, Vinetz, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832958/
https://ncbi.nlm.nih.gov/pubmed/20056606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063388
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