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An Anti-Chitinase Malaria Transmission–Blocking Single-Chain Antibody as an Effector Molecule for Creating a Plasmodium falciparum–Refractory Mosquito
Indirect evidence has suggested the existence of a second chitinase gene, PgCHT2, in the avian malaria parasite Plasmodium gallinaceum. We have now identified PgCHT2 as the orthologue of the P. falciparum chitinase gene PfCHT1, a malaria transmission–blocking target. Computational phylogenetic evide...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265778/ https://ncbi.nlm.nih.gov/pubmed/16088838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/432552 |
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