Androgen Receptor Survival Signaling Is Blocked by Anti-β2-microglobulin Monoclonal Antibody via a MAPK/Lipogenic Pathway in Human Prostate Cancer Cells

A new cis-acting element, sterol regulatory element-binding protein-1 (SREBP-1) binding site, within the 5′-flanking human androgen receptor (AR) promoter region and its binding transcription factor, SREBP-1, was identified to regulate AR transcription in AR-positive human prostate cancer cells. We...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huang, Wen-Chin, Zhau, Haiyen E., Chung, Leland W. K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832945/
https://ncbi.nlm.nih.gov/pubmed/20071336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092759
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