β2-Microglobulin Signaling Blockade Inhibited Androgen Receptor Axis and Caused Apoptosis in Human Prostate Cancer Cells

PURPOSE: β2-Microglobulin (β2M) has been shown to promote osteomimicry and the proliferation of human prostate cancer cells. The objective of this study is to determine the mechanism by which targeting β2M using anti-β2M antibody inhibited growth and induced apoptosis in prostate cancer cells. EXPER...

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Hlavní autoři: Huang, Wen-Chin, Havel, Jonathan J., Zhau, Haiyen E., Qian, Wei Ping, Lue, Hui-Wen, Chu, Chia-Yi, Nomura, Takeo, Chung, Leland W.K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032570/
https://ncbi.nlm.nih.gov/pubmed/18765525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0793
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