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Adenovirus-Specific Human T cells are Pervasive, Polyfunctional, and Cross Reactive
Pre-existing immunity to adenovirus (Ad) reduces the efficacy of Ad-based vaccines. The goal of this study was to define the prevalence, magnitude, functionality and phenotype of Ad-specific human T cells directly ex vivo. To study the magnitude of T-cell responses to Ad, we developed a highly repro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832841/ https://ncbi.nlm.nih.gov/pubmed/20188249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.10.091 |
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