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CASPASE 2-MEDIATED TUMOR SUPPRESSION INVOLVES SURVIVIN GENE SILENCING

One of the pivotal functions of endogenous tumor suppression is to oppose aberrant cell survival, but the molecular requirements of this process are not completely understood. Here, we show that caspase 2, a death effector with largely unknown functions, represses transcription of the survivin gene,...

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Detalhes bibliográficos
Main Authors: Guha, Minakshi, Xia, Fang, Raskett, Christopher M., Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832727/
https://ncbi.nlm.nih.gov/pubmed/19935698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.428
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