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ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration
Endoglin, an endothelial cell-specific transforming growth factor-β (TGF-β) superfamily coreceptor, has an essential role in angiogenesis. Endoglin-null mice have an embryonic lethal phenotype due to defects in angiogenesis and mutations in endoglin result in the vascular disease hereditary hemorrha...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832549/ https://ncbi.nlm.nih.gov/pubmed/20042635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp327 |
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