Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis

Hypoxia-inducible factors (HIFs), in particular HIF-1α, have been implicated in tumor biology. However, HIF target genes in the esophageal tumor microenvironment remain elusive. Gene expression profiling was performed upon hypoxia-exposed non-transformed immortalized human esophageal epithelial cell...

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Bibliographische Detailangaben
Hauptverfasser: Lee, James J., Natsuizaka, Mitsuteru, Ohashi, Shinya, Wong, Gabrielle S., Takaoka, Munenori, Michaylira, Carmen Z., Budo, Daniela, Tobias, John W., Kanai, Michiyuki, Shirakawa, Yasuhiro, Naomoto, Yoshio, Klein-Szanto, Andres J.P., Haase, Volker H., Nakagawa, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832548/
https://ncbi.nlm.nih.gov/pubmed/20042640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp326
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