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Nuclear Receptor SHP, a Death Receptor That Targets Mitochondria, Induces Apoptosis and Inhibits Tumor Growth

Small heterodimer partner (SHP) is an epigenetically regulated nuclear transcriptional repressor that suppresses the development of liver cancer by inhibiting cellular growth. Here we report a novel cytoplasmic function of SHP through its regulation of mitochondrial activity. SHP is a pivotal cell d...

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Detalhes bibliográficos
Main Authors: Zhang, Yuxia, Soto, Jamie, Park, Kyungtae, Viswanath, Gunda, Kuwada, Scott, Abel, E. Dale, Wang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832505/
https://ncbi.nlm.nih.gov/pubmed/20065042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01076-09
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