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Yeast Exonuclease 5 Is Essential for Mitochondrial Genome Maintenance

Yeast exonuclease 5 is encoded by the YBR163w (DEM1) gene, and this gene has been renamed EXO5. It is distantly related to the Escherichia coli RecB exonuclease class. Exo5 is localized to the mitochondria, and EXO5 deletions or nuclease-defective EXO5 mutants invariably yield petites, amplifying ei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burgers, Peter M., Stith, Carrie M., Yoder, Bonita L., Sparks, Justin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832504/
https://ncbi.nlm.nih.gov/pubmed/20086101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01321-09
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