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14-3-3τ Regulates Ubiquitin-Independent Proteasomal Degradation of p21, a Novel Mechanism of p21 Downregulation in Breast Cancer

14-3-3 proteins regulate many cellular functions, including proliferation. However, the detailed mechanisms by which they control the cell cycle remain to be fully elucidated. We report that one of the 14-3-3 isoforms, 14-3-3τ, is required for the G(1)/S transition through its role in ubiquitin-inde...

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Detalhes bibliográficos
Main Authors: Wang, Bing, Liu, Kang, Lin, Hui-Yi, Bellam, Naresh, Ling, Shiyun, Lin, Weei-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832502/
https://ncbi.nlm.nih.gov/pubmed/20086099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01335-09
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