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Identification and Analysis of the Interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae

Cap hydrolysis is a critical control point in the life of eukaryotic mRNAs and is catalyzed by the evolutionarily conserved Dcp1-Dcp2 complex. In Saccharomyces cerevisiae, decapping is modulated by several factors, including the Lsm family protein Edc3, which directly binds to Dcp2. We show that Edc...

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Bibliographic Details
Main Authors: Harigaya, Yuriko, Jones, Brittnee N., Muhlrad, Denise, Gross, John D., Parker, Roy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832485/
https://ncbi.nlm.nih.gov/pubmed/20086104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01305-09
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