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Effects of Antibiotics and a Proto-oncogene Homolog on Destruction of Protein Translocator SecY
Protein secretion occurs via translocation by the evolutionarily-conserved Sec complex. LacZ hybrid proteins have long been used to study translocation in Escherichia coli. Some LacZ hybrids were thought to block secretion by physically jamming the Sec complex leading to cell death. We found that ja...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832214/ https://ncbi.nlm.nih.gov/pubmed/19661432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1172221 |
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