ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells

The metalloprotease ADAMTS9 participates in melanoblast development and is a tumor suppressor in esophageal and nasopharyngeal cancer. ADAMTS9 null mice die before gastrulation, but, ADAMTS9(+/−) mice were initially thought to be normal. However, when congenic with the C57Bl/6 strain, 80% of ADAMTS9...

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Detalhes bibliográficos
Main Authors: Koo, Bon-Hun, Coe, David M., Dixon, Laura J., Somerville, Robert P.T., Nelson, Courtney M., Wang, Lauren W., Young, Mary Elizabeth, Lindner, Daniel J., Apte, Suneel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832168/
https://ncbi.nlm.nih.gov/pubmed/20093484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090655
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