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Total Synthesis of (+)-Fendleridine (Aspidoalbidine) and (+)-1-Acetylaspidoalbidine
A total synthesis of the Aspidosperma alkaloids (+)-fendleridine (1) and (+)-1-acetylaspidoalbidine (2) is detailed, providing access to both enantiomers of the natural products and establishing their absolute configuration. Central to the synthetic approach is a powerful intramolecular [4 + 2]/[3 +...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832086/ https://ncbi.nlm.nih.gov/pubmed/20148585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908819q |
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