Phylogenomic Analyses Reveal the Evolutionary Origin of the Inhibin α-Subunit, a Unique TGFβ Superfamily Antagonist

Transforming growth factor-beta (TGFβ) homologues form a diverse superfamily that arose early in animal evolution and control cellular function through membrane-spanning, conserved serine-threonine kinases (RII and RI receptors). Activin and inhibin are related dimers within the TGFβ superfamily tha...

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Detalhes bibliográficos
Main Authors: Zhu, Jie, Braun, Edward L., Kohno, Satomi, Antenos, Monica, Xu, Eugene Y., Cook, Robert W., Lin, S. Jack, Moore, Brandon C., Guillette, Louis J., Jardetzky, Theodore S., Woodruff, Teresa K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832003/
https://ncbi.nlm.nih.gov/pubmed/20209104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009457
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