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The Implications of Using a Physiologically Based Pharmacokinetic (PBPK) Model for Pesticide Risk Assessment

BACKGROUND: A physiologically based pharmacokinetic (PBPK) model would make it possible to simulate the dynamics of chemical absorption, distribution, metabolism, and elimination (ADME) from different routes of exposures and, in theory, could be used to evaluate associations between exposures and bi...

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Detalhes bibliográficos
Main Authors: Lu, Chensheng, Holbrook, Christina M., Andres, Leo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831956/
https://ncbi.nlm.nih.gov/pubmed/20056589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901144
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