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Regulation Mechanisms and Signaling Pathways of Autophagy

Autophagy is a process of self-degradation of cellular components in which double-membrane autophagosomes sequester organelles or portions of cytosol and fuse with lysosomes or vacuoles for breakdown by resident hydrolases. Autophagy is upregulated in response to extra- or intracellular stress and s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: He, Congcong, Klionsky, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831538/
https://ncbi.nlm.nih.gov/pubmed/19653858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-102808-114910
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