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Mammalian autophagy: core molecular machinery and signaling regulation

Autophagy, a cellular catabolic pathway, is evolutionarily conserved from yeast to mammals. Central to this process is the formation of autophagosomes, double-membrane vesicles responsible for delivering long-lived proteins and excess or damaged organelle into the lysosome for degradation and reuse...

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Detalhes bibliográficos
Main Authors: Yang, Zhifen, Klionsky, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854249/
https://ncbi.nlm.nih.gov/pubmed/20034776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2009.11.014
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