Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase

The ancient and ubiquitous aminoacyl-tRNA synthetases constitute a valuable model system for studying early evolutionary events. So far, the evolutionary relationship of tryptophanyl- and tyrosyl-tRNA synthetase (TrpRS and TyrRS) remains controversial. As TrpRS and TyrRS share low sequence homology...

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Autors principals: Dong, Xianchi, Zhou, Minyun, Zhong, Chen, Yang, Bei, Shen, Ning, Ding, Jianping
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831299/
https://ncbi.nlm.nih.gov/pubmed/19942682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1053
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