The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide

Ebola virus causes rapidly progressive haemorrhagic fever, which is associated with severe immuosuppression. In infected dendritic cells (DCs), Ebola virus replicates efficiently and inhibits DC maturation without inducing cytokine expression, leading to impaired T-cell proliferation. However, the u...

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Bibliografiske detaljer
Main Authors: Jin, Huali, Yan, Zhipeng, Prabhakar, Bellur S., Feng, Zongdi, Ma, Yijie, Verpooten, Dustin, Ganesh, Balaji, He, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2010
Fag:
Animal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831215/
https://ncbi.nlm.nih.gov/pubmed/19828757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.017343-0
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