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HER3 comes of age; New insights into its functions and role in signaling, tumor biology, and cancer therapy

The human epidermal growth family (HER) of tyrosine kinase receptors underly the pathogenesis of many types of human cancer. The oncogenic functions of three of the HER proteins can be unleashed through amplification, overexpression, or mutational activation. This has formed the basis for the develo...

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Autores principales: Campbell, Marcia R., Amin, Dhara, Moasser, Mark M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831167/
https://ncbi.nlm.nih.gov/pubmed/20179223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1218
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