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GPCR Trafficking to the Plasma Membrane: Insights for Pharmacoperone Drugs
G protein-coupled receptors (GPCRs) are among the most common potential targets for pharmacological design. Synthesized in the endoplasmic reticulum (ER), they interact with endogenous chaperones which assist in folding (or may retain incorrectly folded proteins) and are transferred to the plasma me...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831145/ https://ncbi.nlm.nih.gov/pubmed/20005736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2009.11.003 |
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