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Ligand-Free Open–Closed Transitions of Periplasmic Binding Proteins: the Case of Glutamine-Binding Protein
The ability to undergo large-scale domain rearrangements is essential for the substrate binding function of periplasmic binding proteins (PBPs), which are indispensable for nutrient uptake in Gram-negative bacteria. Crystal structures indicate that PBPs typically adopt either an “open” unliganded co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831130/ https://ncbi.nlm.nih.gov/pubmed/20141110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902045p |
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