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R-Ras regulates β(1)-integrin trafficking via effects on membrane ruffling and endocytosis
BACKGROUND: Integrin-mediated cell adhesion and spreading is dramatically enhanced by activation of the small GTPase, R-Ras. Moreover, R-Ras localizes to the leading edge of migrating cells, and regulates membrane protrusion. The exact mechanisms by which R-Ras regulates integrin function are not fu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830936/ https://ncbi.nlm.nih.gov/pubmed/20167113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-14 |
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