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Brain-water diffusion coefficients reflect the severity of inherited prion disease
OBJECTIVE: Inherited prion diseases are progressive neurodegenerative conditions, characterized by cerebral spongiosis, gliosis, and neuronal loss, caused by mutations within the prion protein (PRNP) gene. We wished to assess the potential of diffusion-weighted MRI as a biomarker of disease severity...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Academy of Neurology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830920/ https://ncbi.nlm.nih.gov/pubmed/20177119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181d0cc47 |
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