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The crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism
Cytochrome P450 (CYP) 24A1 catalyzes the side-chain oxidation of the hormonal form of vitamin D. Expression of CYP24A1 is up-regulated to attenuate vitamin-D signaling associated with calcium homeostasis and cellular growth processes. The development of therapeutics for disorders linked to vitamin D...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830900/ https://ncbi.nlm.nih.gov/pubmed/19961857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.057 |
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